MIT-Harvard Center of Cancer Nanotechnology
Massachusetts Institute of Technology and Harvard University CCNE

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Center Investigators

Robert Langer, Ph.D.
Principal Investigator

Ralph Weissleder, M.D., Ph.D.
Principal Investigator

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Projects

• Project 1: Targeted Polymeric Nanoparticles for Cancer Therapeutic Applications
• Project 2: Treatment of Cancer with siRNA Delivered by Nanoparticles
• Project 3: Development of Clinical-Grade, Targeted Magnetic Nanoparticles
• Project 4: Discrete Sensor Devices for Determining Cancer Targets
• Project 5: Novel Semiconducting Nanocrystals for Cancer Detection

Pilot Projects:

1. Nanoparticle labels for high-sensitivity mass detection of cancer biomarkers
2. Microfluidic sorting of circulating tumor cells
3. Nanomodels of metastatic cancer
4. Hybrid integrated circuit/ microfluidic chips for the manipulation of cells
5. Ultrasensitive chemical probing at the single molecule leve using surface enhanced Raman scattering in local optical fields of gold nanoparticles
6. Functionalized linear-dendritic diblock copolymers for targeted, tumor-selective nucleic acid delivery
7. Targeted nanoparticles for siRNA deliver in cancer
8. Nanowire, nanolaser as optical probe for high resolution cellular imaging and manipulation