Centers of Cancer Nanotechnology Excellence (CCNEs)
Carolina Center of Cancer Nanotechnology Excellence
The University of North Carolina at Chapel Hill
Center Overview
The Carolina CCNE focuses on improving cancer disease control and management utilizing innovative and cutting edge nanotechnologies, such as PRINT (Particle Replication on Non-Wetting Templates) nanoparticles and carbon-nanotube-based x-ray sources, to enhance treatment and early detection of lung, brain and breast cancer. The Carolina CCNE has proposed five research projects in two key areas: nanoparticle based delivery of siRNA and chemotherapy & carbon nanotube based radiation therapy and early detection.
Center Investigators
Joseph DeSimone, Ph.D.
Principal Investigator
Joel Tepper, M.D.
Principal Investigator
For more information about Carolina Center of Cancer Nanotechnology Excellence visit our website at: http://carolinaccne.unc.edu/.
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Affiliated Institutions
Projects
- Project 1: PRINT Nanoparticles: "Calibration Quality" Nano-tools for Studying Particle Biodistribution
- Project 2: Ras Pathway siRNA in Lung Cancer
- Project 3: Translational Nanosystems for Improved Lung Cancer Treatment with Small Molecules
- Project 4: Compact Micro-Beam Radiation Therapy in Brain Cancer
- Project 5: Digital Breast Tomosynthesis System
Cores
- Core A: Analytical and Pharmacokinetics
- Core B: Targeting Ligand
- Core C: Animal Imaging
