Center for Translational Cancer Nanomedicine
Northeastern University

Center Overview

The main objective of the Center for Translational Cancer Nanomedicine is to develop, test pre-clinically in vitro and in vivo, characterize, scale up, and manufacture under Good Manufacturing Practice (GMP) conditions test batches of the most promising nanopreparations for cancer, with a particular focus on lung, ovarian, and pancreatic cancer. Nanocarriers will include polymeric micelles, liposomes, polymeric particles, and dendrimers, while the drugs to be used will include pro-apoptotic agents, DNA, and siRNA together with diagnostic labels.

Center Investigators

Vladimir Torchilin, Ph.D., D.Sc.
Principal Investigator

Nahum Goldberg, M.D.
Principal Investigator

For more information about the Center for Translational Cancer Nanomedicine visit our website at: http://www.northeastern.edu/ccne/.

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Affiliated Institutions

Projects

Project 1: Combined Targeted Micellar Preparations of Novel Proapoptotic Drug and siRNA for Cancer
Project 2: Combined Cancer Therapy with RF Ablation and Drug-Loaded Nanopreparations
Project 3: Multi-Modal Gene Therapy for Pancreatic Cancer Using Targeted Nanovectors
Project 4: Development and High-Throughput Screening of Targeted Anti-Cancer Nanomedicines

Cores