Dartmouth Center of Cancer Nanotechnology Excellence
The Dartmouth CCNE uses novel biocompatible magnetic nanoparticles targeted to tumors to destroy or severely damage the tumors when an alternating magnetic field is applied. Researchers also examine the synergy of combining this approach with chemotherapy to produce anti-tumor immunity. This CCNE focuses on breast cancer and ovarian cancer treatments, but the approaches developed can potentially be used for any type of cancer.
Ian Baker, D.Phil.
Keith Paulsen, Ph.D.
- Project 1: Optimization of Nanoparticle Targeting in Ovarian and Breast Cancer
- Project 2: Spectroscopic Quantification of Ligand Binding In Vivo
- Project 3: Optimization of Magnetic Nanoparticle Breast Cancer Treatment
- Project 4: Magnetic Nanoparticle Immunotherapy against Ovarian Cancer
- Core A: Nanoparticle Development, Production, and Characterization
- Core B: Toxicology, Pathology, and Biodistribution
- Core C: Biostatistics, Data Analysis, and Computation