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Nanotech News


December 2012

Additional Publications of Note for December

Therapeutics

Layer-by-layer nanoparticles with a pH-sheddable layer for in vivo targeting of tumor hypoxia
ACS Nano
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Folate-targeted nanoparticle delivery of chemo- and radiotherapeutics for the treatment of ovarian cancer peritoneal metastasis
Biomaterials
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Redox-responsive nanoparticles from the single disulfide bond-bridged block copolymer as drug carriers for overcoming multidrug resistance in cancer cells
Bioconjugate Chemistry
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Gold nanoparticles surface-functionalized with paclitaxel drug and biotin receptor as theranostic agents for cancer therapy
Biomaterials
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Conatumumab (AMG 655) coated nanoparticles for targeted pro-apoptotic drug delivery
Biomaterials
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Synthetic modification of carboxymethylcellulose and use thereof to prepare a nanoparticle forming conjugate of docetaxel for enhanced cytotoxicity against cancer cells
Bioconjugate Chemistry
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Targeted anticancer prodrug with mesoporous silica nanoparticles as vehicles
Nanotechnology
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A polymeric nanoparticle encapsulated small molecule inhibitor of hedgehog signaling (NanoHHI) bypasses secondary mutational resistance to smoothened antagonists
Molecular Cancer Therapeutics
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Multiple Presentation of Scfv800E6 on silica nanospheres enhances targeting efficiency toward her-2 receptor in breast cancer cells
Bioconjugate Chemistry
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Enhanced drug loading on magnetic nanoparticles by layer-by-layer assembly using drug conjugates: blood compatibility evaluation and targeted drug delivery in cancer cells
Langmuir
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Targeted delivery of cisplatin to lung cancer using ScFvEGFR-heparin-cisplatin nanoparticles
ACS Nano
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Neutron-activatable holmium-containing mesoporous silica nanoparticles as a potential radionuclide therapeutic agent for ovarian cancer
Journal of Nuclear Medicine
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A gold nanoparticle platform for the delivery of functional microRNAs into cancer cells
Biomaterials
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Overcoming limitations in nanoparticle drug delivery: triggered, intravascular release to improve drug penetration into tumors
Cancer Research
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Lipid-functionalized dextran nanosystems to overcome multidrug resistance in cancer
Clinical Orthopaedics and Related Research
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Synergistic cytotoxicity of irinotecan and cisplatin in dual-drug targeted polymeric nanoparticles
Nanomedicine
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DNA nanotherapy for pre-neoplastic cervical lesions
Gynecologic Oncology
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Imaging

Highly biocompatible TiO(2):Gd(3+) nano-contrast agent with enhanced longitudinal relaxivity for targeted cancer imaging
Nanoscale
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SPIO-enhanced magnetic resonance imaging for the detection of metastases in sentinel nodes localized by computed tomography lymphography in patients with breast cancer
Annals of Surgical Oncology
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Noninvasive optical imaging of nanomedicine biodistribution
ACS Nano
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Diagnostics & Biosensors

Targeted luminescent near-infrared polymer-nanoprobes for in vivo imaging of tumor hypoxia
Analytical Chemistry
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Classification of the lung cancer histology by gold nanoparticle sensors
Nanomedicine: Nanotechnology, Biology and Medicine
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Nano Devices & Materials

Dendrimer-mediated multivalent binding for the enhanced capture of tumor cells
Angewandte Chemie International Edition
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Microchip-based immunomagnetic detection of circulating tumor cells
Lab on a Chip
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Integration of intra- and extravasation in one cell-based microfluidic chip for the study of cancer metastasis
Lab on a Chip
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Novel microwave-assisted solvothermal synthesis of NaYF4:Yb,Er upconversion nanoparticles their application in cancer cell imaging
Langmuir
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pH titratable superparamagnetic iron oxide for improved nanoparticle retention in acidic tumor microenvironments
ACS Nano
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Nano Biology

89Zr labeled dextran nanoparticles enable in vivo macrophage imaging
Bioconjugate Chemistry
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Tumor accumulation of NIR fluorescent PEG–PLA nanoparticles: impact of particle size and human xenograft tumor model
ACS Nano
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